Quarantine protocols mean Red Cadeaux will have a new home for his fifth attempt at the Melbourne Cup.

The three-time Melbourne Cup runner-up has a barn named in his honour at Werribee where the international spring carnival contenders are housed.

But this year, he will have to stay in a different complex named for 1993 Melbourne Cup winner Vintage Crop.

The number of horses coming to Australia this year, especially in the second shipment due on October 10 has forced a reshuffle of stables.

Racing Victoria's racing operations manager Paul Bloodworth said the way the shipments worked out this year means Red Cadeaux could not be in his usual barn.

Red Cadeaux, stablemates Trip To Paris and Manndawi, Max Dynamite, Snow Sky and Quest For More are due in Melbourne on Saturday afternoon.

"The way it's worked with the two shipment dates this year we're having to split this first one between locals returning and or staying on and those that are competing," Bloodworth said.

"The two Japanese horses have gone into Vintage Crop and the six coming out, of which Red Cadeaux is one, will join them.

"The others, which are locals or those staying on including Criterion, will go into Newminster and finish their quarantine on Caulfield Guineas day."

Bloodworth said the second shipment of horses, which could total up to 14, would in the afternoon of October 10, replace those horses that leave that morning.